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・ GDP (musician)
・ GDP deflator
・ GDP density
・ GDP-4-dehydro-6-deoxy-D-mannose reductase
・ GDP-4-dehydro-D-rhamnose reductase
・ GDP-6-deoxy-D-talose 4-dehydrogenase
・ GDP-D-glucose phosphorylase
・ GDP-fucose protein O-fucosyltransferase 1
・ GDP-fucose protein O-fucosyltransferase 2
・ GDP-glucosidase
・ GDP-L-fucose synthase
・ GDP-L-galactose phosphorylase
・ GDP-linked bond
・ GDP-mannose 3,5-epimerase
・ GDP-mannose 4,6-dehydratase
GDP-mannose 6-dehydrogenase
・ GDPase
・ GDPS (disambiguation)
・ GDR (disambiguation)
・ GDR championship women's basketball
・ GDR Children of Namibia
・ GDR Union of Journalists
・ Gdraymah
・ GDRC
・ GDRT
・ GDS
・ GDSII
・ GDT
・ GDT speedster
・ GDU


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GDP-mannose 6-dehydrogenase : ウィキペディア英語版
GDP-mannose 6-dehydrogenase

In enzymology, a GDP-mannose 6-dehydrogenase () is an enzyme that catalyzes the chemical reaction
:GDP-D-mannose + 2 NAD+ + H2O \rightleftharpoons GDP-D-mannuronate + 2 NADH + 2 H+
The 3 substrates of this enzyme are GDP-D-mannose, NAD+, and H2O, whereas its 3 products are GDP-D-mannuronate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is GDP-D-mannose:NAD+ 6-oxidoreductase. Other names in common use include guanosine diphosphomannose dehydrogenase, GDP-mannose dehydrogenase, guanosine diphosphomannose dehydrogenase, and guanosine diphospho-D-mannose dehydrogenase. This enzyme participates in fructose and mannose metabolism.
This protein may use the morpheein model of allosteric regulation.
==Structural studies==

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes , , and .

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